Rifampin and tobramycin combination with PMMA antibiotic cement.

Likine, Elive F; Seligson, David · Eur J Orthop Surg Traumatol · 2019

basic_science · Level V

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Abstract

Rifampin is a powerful antibiotic used in the treatment of biofilm-forming bacteria with studies supporting its use in PMMA cement. However, it has not been widely accepted for its use in PMMA cement due to a perception that it is unable to solidify in a timely manner. The technique described consists of ratio of aminoglycoside and rifampin that reduces time to solidification to approximately 15-20 min.

Medical subject headings