Magnitude of Clinical Benefit of Cancer Drugs Approved by the US Food and Drug Administration Based on Single-Arm Trials.

Tibau, Ariadna; Molto, Consolación; Borrell, Maria; Del Paggio, Joseph C; Barnadas, Agustí; Booth, Christopher M; Amir, Eitan · JAMA Oncol · 2018

case_series · Level IV

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Abstract

This study uses the European Society of Medical Oncology Magnitude of Clinical Benefit Scale to evaluate the clinical benefit of anticancer drugs that gained approval by the US Food and Drug Administration based on single-arm rather than randomized clinical trials.

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