Amnion-Based Scaffold with Enhanced Strength and Biocompatibility for <i>In Vivo</i> Vascular Repair.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 30284966.
- Also identified by DOI 10.1089/ten.TEA.2018.0175.
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Abstract
This study aimed at developing an amnion-based scaffold suitable for vascular tissue engineering applications and <i>in vivo</i> usage. We successfully produced a multilayered scaffold with improved biomechanical properties and biocompatibility for <i>in vivo</i> vascular implantation. Our approach not only offers an allogeneic "off-the-shelf" solution for clinical use but also it provides the possibility of personalized medicine using a patient's own amnion and stem cells for the production of tissue engineered grafts for reconstructive heart surgery.
Medical subject headings
- Amnion
- Myocardium
- Tissue Engineering
- Tissue Scaffolds