SnapShot: RNA Structure Probing Technologies.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 30290145.
- Also identified by DOI 10.1016/j.cell.2018.09.024 and PMC identifier 6582637.
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Abstract
Chemical probing coupled to high-throughput sequencing offers a flexible approach to uncover many aspects of RNA structure relevant to its cellular function. With a wide variety of chemical probes available that each report on different features of RNA molecules, a broad toolkit exists for investigating in vivo and in vitro RNA structure and interactions with other molecules.
Medical subject headings
- High-Throughput Nucleotide Sequencing
- RNA