Hematopoietic Stem Cells Rock Around The Clock: Circadian Fate Control via TNF/ROS Signals.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 30290172.
- Also identified by DOI 10.1016/j.stem.2018.09.002.
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Abstract
Hematopoietic stem cell function is closely tied to circadian rhythms. In this issue of Cell Stem Cell, Golan et al. (2018) identify crosstalk between circadian hormone signals, the inflammatory cytokine TNF, and bone marrow macrophages as a key regulator of HSC proliferation, differentiation, and self-renewal in the bone marrow.
Medical subject headings
- Hematopoiesis
- Hematopoietic Stem Cells