New Recipes for Myelinating Oligodendrocytes.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 30290175.
- Also identified by DOI 10.1016/j.stem.2018.09.011.
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Abstract
While myelinating oligodendrocytes are attractive candidates for cell-based regenerative therapies, producing them in adequate quantities and regulation of progenitor differentiation pathways has proven limiting. Recently, Hubler et al. (2018) and Madhavan et al. (2018) generated cerebral organoids with myelinating oligodendrocytes and manipulated sterol pathway small molecules to promote myelin synthesis.
Medical subject headings
- Myelin Sheath
- Oligodendroglia