Pirfenidone-Induced Sarcoid-Like Reaction: A Novel Complication.

Kolaitis, Nicholas A; Kukreja, Jasleen; Jones, Kirk D; Hays, Steven R; Leard, Lorriana E · Chest · 2018

case_report · Level V

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Abstract

Idiopathic pulmonary fibrosis is the most common idiopathic interstitial pneumonia. Prognosis is poor with a median survival <3 years. Pirfenidone is one of two US Food and Drug Administration-approved medications that slow disease progression. We describe the development of lymphadenopathy or a sarcoid-like reaction following initiation of pirfenidone, a complication not previously reported.

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