Mechanical properties and cytotoxicity of hierarchical carbon fiber-reinforced poly (ether-ether-ketone) composites used as implant materials.

Abstract

Weak mechanical properties affect the application of PEEK as an implant. Carbon fiber (CFR) reinforcement provides an excellent solution to improve the mechanical strength of PEEK and to provide perfect matching of elastic modulus between CFR-PEEK composites and human bone. To investigate the effect of carbon fiber content on the mechanical, thermal properties and cytotoxicity of CFR reinforced PEEK composites, a series of CFR-PEEK composites with different carbon fiber content (25 wt%, 30 wt%, 35 wt%, 40 wt%) was prepared in this work. Thermal decomposition behavior and melting temperature were studied by thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC), respectively. Subsequently, mechanical properties including bending strength, compressive strength, impact strength and hardness were tested respectively. Afterwards, the fracture morphology of the bending test samples was observed by scanning electron microscopy (SEM). In addition, murine fibroblast L929 cells were adopted for cytotoxicity test by CCK-8 assay in vitro, and the morphology of cells was observed by inverted fluorescence microscope simultaneously, cell compatibility of CFR-PEEK composites was tested.