On-chip photodynamic therapy - monitoring cell metabolism using electrochemical microsensors.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 30310892.
- Also identified by DOI 10.1039/c8lc00799c.
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Abstract
We introduce a new system which combines metabolic monitoring using electrochemical microsensors with photodynamic therapy on-chip for the first time. Oxygen consumption of T-47D breast cancer cells was measured during therapy with protoporphyrin IX. We determined the efficacy of the therapy and revealed its recovery effects, which underlines the high relevance of continuous monitoring.
Medical subject headings
- Cells
- Photochemotherapy
- Tissue Array Analysis