Minimal Clinically Important Improvement of Routine Assessment of Patient Index Data 3 in Rheumatoid Arthritis.
prospective_cohort · Level II
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- Record sourced from PubMed, PMID 30323010.
- Also identified by DOI 10.3899/jrheum.180153 and PMC identifier 6314888.
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Abstract
To estimate minimal clinically important improvement (MCII) of RAPID-3 (Routine Assessment of Patient Index Data 3) in rheumatoid arthritis (RA). RAPID-3 was computed before and after treatment escalation in a prospective study of adults with active RA. Patient judgment of improvement was used as the standard for a receiver-operating characteristic curve, from which MCII was estimated. Mean RAPID-3 improved from 16.3 to 11.1 between visits. MCII was -3.8 based on simultaneously optimized sensitivity and specificity, -3.5 using the 0.80 specificity criterion, and -4.1 using the Youden index. RAPID-3 improvement of 3.8/30 units appears clinically meaningful.
Medical subject headings
- Antirheumatic Agents
- Arthritis, Rheumatoid
- Patient Satisfaction