Maternal Measles Antibodies and Their Influence on All-cause Mortality Following Measles Vaccination: An Alternative to Measure Very Low Maternal Antibody Levels.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 30329030.
- Also identified by DOI 10.1093/cid/ciy900.
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Abstract
It was previously shown by hemagglutination inhibition that measles vaccination in the presence of maternal measles antibodies was associated with reduced all-cause mortality. We confirmed this serological association using a multiplexed immunoassay as a sensitive alternative and estimated a threshold concentration (28.7 mIU/mL) that correlates with lower all-cause mortality (P = .02).
Medical subject headings
- Antibodies, Viral
- Immunity, Maternally-Acquired
- Immunoassay
- Measles
- Measles Vaccine