Glioma Cell Secretion: A Driver of Tumor Progression and a Potential Therapeutic Target.

Almiron Bonnin, Damian A; Havrda, Matthew C; Israel, Mark A · Cancer Res · 2018

review · Level V

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Abstract

Cellular secretion is an important mediator of cancer progression. Secreted molecules in glioma are key components of complex autocrine and paracrine pathways that mediate multiple oncogenic pathologies. In this review, we describe tumor cell secretion in high-grade glioma and highlight potential novel therapeutic opportunities. <i>Cancer Res; 78(21); 6031-9. ©2018 AACR</i>.

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