Plasma tryptase elevation during aspirin-induced reactions in aspirin-exacerbated respiratory disease.

Cahill, Katherine N; Murphy, Katherine; Singer, Joseph; Israel, Elliot; Boyce, Joshua A; Laidlaw, Tanya M · J Allergy Clin Immunol · 2019

Level V

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Abstract

Plasma tryptase elevation during aspirin-induced respiratory reactions occurs in 50% of reactions despite CysLT<sub>1</sub>R antagonist prophylaxis and identifies lung function decline and extra-respiratory symptoms in aspirin-exacerbated respiratory disease (AERD).

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