Partial Meniscus Replacement with a Collagen-Hyaluronan Infused Three-Dimensional Printed Polymeric Scaffold.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 30351200.
- Also identified by DOI 10.1089/ten.TEA.2018.0160 and PMC identifier 6916120.
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Abstract
The only FDA-approved partial meniscus scaffold, the Collagen Meniscus Implant (CMI), is not approved for reimbursement by government and only reimbursable by certain private insurers. Scaffolds with improved mechanical properties and greater efficacy are needed. A previous study (Ghodbane, <i>et al.</i> DOI: 10.1002/jbm.b.34331) demonstrated the ability of our novel acellular, off-the shelf scaffold to restore knee biomechanics following partial meniscectomy, which could potentially decrease the risk of osteoarthritis following partial meniscectomy, providing the motivation for this study. This article presents a first-in-animal feasibility study.
Medical subject headings
- Arthroplasty, Replacement
- Collagen
- Hyaluronic Acid
- Meniscus
- Polymers
- Printing, Three-Dimensional
- Tissue Scaffolds