Cancer stem cells in esophageal cancer and response to therapy.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 30368777.
- Also identified by DOI 10.1002/cncr.31697 and PMC identifier 6234092.
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Abstract
Cancer stem cells (CSCs) in esophageal cancer have a key role in tumor-initiation, progression, metastases, immune evasion, and therapy resistance. CSCs can be characterized by unique biomarkers, however, there exists an immense complexity of changing characteristics driven by tumor evolution and exposure to therapy. Attempts to target CSCs are ongoing but more in depth research is necessary.
Medical subject headings
- Biomarkers, Tumor
- Esophageal Neoplasms
- Neoplastic Stem Cells