Lymph node involvement: Positive about the role of the recurrence score in estrogen-driven breast cancer?

Kalinsky, Kevin; O'Regan, Ruth M · Cancer · 2019

editorial · Level V

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Abstract

It remains unclear whether there is clinical utility for withholding chemotherapy in HR+/HER2-, node-positive breast cancer based upon the 21-gene Recurrence Score. While we await the results from randomized, phase III trials, this editorial addresses additional observational data that suggest there may be a role for this genomic assay in this patient population.

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