Tissue Unit-ed: Lung Cells Team up to Drive Alveolar Macrophage Development.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 30388447.
- Also identified by DOI 10.1016/j.cell.2018.10.031.
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Abstract
Using single-cell RNA sequencing of both immune and non-immune cells in the developing lung, Cohen et al. map candidate cell-cell interactions during alveolar macrophage development. This revealed potential cross-talk between epithelial cells, ILC2s, basophils, and the developing macrophages, which were validated both in vitro and in vivo.
Medical subject headings
- Basophils
- Macrophages, Alveolar