Top to Tail: Anterior-Posterior Patterning Precedes Regional Nervous System Identity.

Simon, Claire S; Hadjantonakis, Anna-Katerina · Cell · 2018

editorial · Level V

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Abstract

In this issue, Metzis et al., demonstrate that in the development of the central nervous system, patterning along the anterior-posterior axis precedes acquisition of neural identity. This contrasts with the prevailing view that neural identity comes first, providing a new window on the origins of the brain and spinal cord.

Medical subject headings