Evaluation of Lowering the P Value Threshold for Statistical Significance From .05 to .005 in Previously Published Randomized Clinical Trials in Major Medical Journals.

Wayant, Cole; Scott, Jared; Vassar, Matt · JAMA · 2018

systematic_review · Level I

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Abstract

This study evaluates primary end points in randomized clinical trials (RCTs) published in 3 major general medical journals to determine how changing the <i>P</i> value threshold for statistical significance from .05 to .005 could affect the interpretation of previously published RCTs.

Medical subject headings