Revisiting the Warburg Effect: Some Tumors Hold Their Breath.

Sanderson, Sydney M; Locasale, Jason W · Cell Metab · 2018

Level V

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Abstract

Studies have shown that tumors commonly exhibit normal or enhanced respiration in addition to glycolytic metabolism. In this issue, Courtney et al. (2018) report a reduction in mitochondrial function in kidney cancer patients and thus a classic "Warburg Effect" that further illustrates the heterogeneity of human cancer metabolism.

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