New aspects of neuroinflammation and neuroimmune crosstalk in the airways.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 30409249.
- Also identified by DOI 10.1016/j.jaci.2018.09.011.
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Abstract
Neuroimmune interaction has long been discussed in the pathogenesis of allergic airway diseases, such as allergic asthma. Mediators released during inflammation can alter the function of both sensory and parasympathetic neurons innervating the airways. Evidence has been provided that the inflammatory response can be altered by various mediators that are released by sensory and parasympathetic neurons and vice versa. Our aim is to demonstrate recent developments in the reciprocal neuroimmune interaction and to include, if available, data from in vivo and clinical studies.
Medical subject headings
- Neuroimmunomodulation
- Neurons
- Respiratory System