Compassionate Use of Cefiderocol as Adjunctive Treatment of Native Aortic Valve Endocarditis Due to Extremely Drug-resistant Pseudomonas aeruginosa.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 30418554.
- Also identified by DOI 10.1093/cid/ciy963 and PMC identifier 6522681.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Serious infections such as endocarditis due to extremely drug-resistance gram-negative bacteria are an increasing challenge. Here, we present successful adjunctive use of cefiderocol for a patient with persistently bacteremic healthcare-associated native aortic valve endocarditis due to an extended-spectrum beta-lactamase-positive Pseudomonas aeruginosa susceptible in vitro only to colistin, following failure of conventional therapeutic options.
Medical subject headings
- Anti-Bacterial Agents
- Aortic Valve
- Cephalosporins
- Drug Resistance, Multiple, Bacterial
- Endocarditis, Bacterial
- Pseudomonas Infections