Second round results from the Manchester 'Lung Health Check' community-based targeted lung cancer screening pilot.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 30420406.
- Also identified by DOI 10.1136/thoraxjnl-2018-212547 and PMC identifier 6585285.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
We report results from the second annual screening round (T1) of Manchester's 'Lung Health Check' pilot of community-based lung cancer screening in deprived areas (undertaken June to August 2017). Screening adherence was 90% (n=1194/1323): 92% of CT scans were classified negative, 6% indeterminate and 2.5% positive; there were no interval cancers. Lung cancer incidence was 1.6% (n=19), 79% stage I, treatments included surgery (42%, n=9), stereotactic ablative radiotherapy (26%, n=5) and radical radiotherapy (5%, n=1). False-positive rate was 34.5% (n=10/29), representing 0.8% of T1 participants (n=10/1194). Targeted community-based lung cancer screening promotes high screening adherence and detects high rates of early stage lung cancer.
Medical subject headings
- Early Detection of Cancer
- Lung Neoplasms
- Mass Screening
- Public Health
- Smoking
- Tomography, X-Ray Computed