Expanding the spectrum of APOL1-related renal disease: de novo collapsing glomerulopathy following kidney transplant.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 30466562.
- Also identified by DOI 10.1016/j.kint.2018.09.006 and PMC identifier 7274138.
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Abstract
Santoriello et al. report a series of 38 cases of de novo collapsing glomerulopathy following kidney transplant. Associations included acute rejection, viral infection, and APOL1 high-risk genotype (the latter in 9 cases). Risk factors for collapsing glomerulopathy included acute rejection, viral infection, acute vaso-occlusive disease, and an African American donor. The data are suggestive of, but do not directly establish, a role for interferon in these associations.
Medical subject headings
- Kidney Diseases
- Kidney Transplantation