Does alanyl-glutamine supplementation offer potential to improve peritoneal dialysate biocompatibility?
rct · Level II
Where this comes from
- Record sourced from PubMed, PMID 30466563.
- Also identified by DOI 10.1016/j.kint.2018.09.012.
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Abstract
Peritoneal dialysis technique survival remains challenging due to peritonitis and long-term alterations to peritoneal membrane function and integrity. Up to now, the development of less bio-incompatible dialysis solutions have not had a major impact on these aspects of the therapy. A novel approach, supplementing dialysis solutions with a cytoprotective additive, alanyl-glutamine, has shown benefits to surrogate biomarkers of cell function in a randomized controlled study.
Medical subject headings
- Peritoneal Dialysis
- Peritonitis