Immunoglobulin G4-Related Disease Association With an Isolated Anterior Mediastinal Tumor.

Yoshikawa, Ryohei; Igai, Hitoshi; Ohsawa, Fumi; Yazawa, Tomohiro; Kamiyoshihara, Mitsuhiro · Ann Thorac Surg · 2019

case_report · Level V

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Abstract

We treated a patient with immunoglobulin G4-related disease (IgG4-RD) exhibiting an isolated anterior mediastinal mass with high 2-[<sup>18</sup>F]-fluoro-2-deoxy-D-glucose accumulation, which mimicked thymoma. The 71-year-old man had a 47-mm anterior mediastinal mass shadow and was referred to our department. Because positron emission tomography revealed the mass to have a high level of 2-[<sup>18</sup>F]-fluoro-2-deoxy-D-glucose accumulation, we diagnosed it as suspected thymoma; thoracoscopic resection of the tumor was then performed. Immunohistologic findings, however, yielded a diagnosis of IgG4-RD. Despite its rarity, IgG4-RD should be borne in mind as a potential diagnosis in case of isolated anterior mediastinal mass shadow.

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