Periodontal Tissue Regeneration Using Brain-Derived Neurotrophic Factor Delivered by Collagen Sponge.

Ramalho, Ilana; Bergamo, Edmara; Lopes, Adolfo; Medina-Cintrón, Camille; Neiva, Rodrigo; Witek, Lukasz; Coelho, Paulo · Tissue Eng Part A · 2019

Level V

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Abstract

The various roles played by brain-derived neurotrophic factor (BDNF) in a multitude of tissues and at different scenarios have rendered BDNF a favorable candidate for improving tissue regeneration. Although the tested formulations of BDNF quantitatively regenerate tissue to a level similar to control groups, it resulted in significantly more instances of full regeneration.

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