Secretin: An Old Hormone with a Burning Secret.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 30500531.
- Also identified by DOI 10.1016/j.cell.2018.11.008 and PMC identifier 9514229.
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Abstract
Most theories of meal-induced thermogenesis involve a gut-brain-brown adipose tissue axis driving sympathetic nervous system-mediated thermogenesis. Li et al. demonstrate that secretin released by the gut after a meal binds to abundant receptors in brown adipose tissue to stimulate thermogenesis, inhibiting food intake and thereby suggesting a novel role for secretin regulating satiety.
Medical subject headings
- Adipose Tissue, Brown
- Secretin