Molecular diagnostics in medical mycology.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 30510235.
- Also identified by DOI 10.1038/s41467-018-07556-5 and PMC identifier 6277409.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Diagnosing fungal infections poses a number of unique problems, including a decline in expertise needed for identifying fungi, and a reduced number of instruments and assays specific for fungal identification compared to that of bacteria and viruses.These problems are exacerbated by the fact that patients with fungal infections are often immunosuppressed, which predisposes to infections from both commonly and rarely seen fungi. In this review, we discuss current and future molecular technologies used for fungal identification, and some of the problems associated with development and implementation of these technologies in today's clinical microbiology laboratories.
Medical subject headings
- DNA, Fungal
- Fungi
- Molecular Diagnostic Techniques
- Mycoses