The Potential Chondrogenic Effect of <i>Eucomis autumnalis</i> Aqueous Extracts on Porcine Adipose-Derived Mesenchymal Stem Cells.

Maepa, Makwese; Ssemakalu, Cornelius Cano; Motaung, Keolebogile Shirley · Tissue Eng Part A · 2019

basic_science · Level V

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Abstract

<i>Eucomis autumnalis</i> is one plant that is used by various traditional healers to alleviate the signs and symptoms associated with osteoarthritis. Although the exact mechanisms remain unknown, we hypothesized that this plant can induce chondrogenesis. In this work, we explored the potential for an aqueous crude extract from <i>E. autumnalis</i> to induce chondrogenesis in porcine adipose-derived mesenchymal stem cells (MSCs). The results reported in our article indicate that the aqueous crude extract from <i>E. autumnalis</i> was able to indeed induce chondrogenesis. Our research is relevant to communities that rely on plant-based remedies for their well-being.

Medical subject headings