A downy mildew effector evades recognition by polymorphism of expression and subcellular localization.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 30518923.
- Also identified by DOI 10.1038/s41467-018-07469-3 and PMC identifier 6281644.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Pathogen co-evolution with plants involves selection for evasion of host surveillance systems. The oomycete Hyaloperonospora arabidopsidis (Hpa) causes downy mildew on Arabidopsis, and race-specific interactions between Arabidopsis accessions and Hpa isolates fit the gene-for-gene model in which host resistance or susceptibility are determined by matching pairs of plant Resistance (R) genes and pathogen Avirulence (AVR) genes. Arabidopsis Col-0 carries R gene RPP4 that confers resistance to Hpa isolates Emoy2 and Emwa1, but its cognate recognized effector(s) were unknown. We report here the identification of the Emoy2 AVR effector gene recognized by RPP4 and show resistance-breaking isolates of Hpa on RPP4-containing Arabidopsis carry the alleles that either are not expressed, or show cytoplasmic instead of nuclear subcellular localization.
Medical subject headings
- Arabidopsis
- Bacterial Proteins
- Cell Nucleus
- Cytoplasm
- Oomycetes
- Plant Diseases
- Virulence Factors