Beta-cell therapies for type 1 diabetes: Transplants and bionics.

Bux Rodeman, Kathryn; Hatipoglu, Betul · Cleve Clin J Med · 2018

review · Level V

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Abstract

Research continues toward the goal of treating type 1 diabetes by replacing insulin-producing beta cells. Ideally, such treatment would be safe and long-lasting and would eliminate the need for subcutaneous insulin replacement. This article reviews the current state of beta-cell replacement through transplant of the whole pancreas or of islet cells. It also looks at the "bionic" pancreas and other future challenges.

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