Duxbling Stem Cells Meet Tumorigenesis.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 30526876.
- Also identified by DOI 10.1016/j.stem.2018.11.020.
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Abstract
Identification of tumor-initiating populations could provide insights into tumor heterogeneity and responses to treatments, but this has proven difficult in most cancers. Now in Cell Stem Cell, Preussner et al. (2018) provide direct evidence that regenerating muscle satellite cells can be transformed to initiate and propagate rhabdomyosarcoma tumors.
Medical subject headings
- Stem Cells
- Tumor Suppressor Protein p53