Virus, Vessel, Victory: A Novel Approach to Tumor Killing.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 30530816.
- Also identified by DOI 10.1158/1078-0432.CCR-18-3441 and PMC identifier 6397697.
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Abstract
Ovarian cancer is intimately dependent on aberrant tumor vasculature. A unique therapeutic approach combining a systemic oncolytic virus with a novel vascular-normalizing agent in ovarian cancer demonstrates the potential to enhance antitumor efficacy through improved delivery of the virus and enhanced infiltration of immune cells into the tumors.<i>See related article by Matuszewska et al., p. 1624</i>.
Medical subject headings
- Oncolytic Virotherapy
- Oncolytic Viruses
- Ovarian Neoplasms