Database of evidence for precision oncology portal.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 30535306.
- Also identified by DOI 10.1093/bioinformatics/bty531 and PMC identifier 6289129.
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Abstract
A database of curated genomic variants with clinically supported drug therapies and other oncological annotations is described. The accompanying web portal provides a search engine with two modes: one that allows users to query gene, cancer type, variant type or position for druggable mutations, and another to search for and to visualize, on three-dimensional protein structures, putative druggable sites that cluster with known druggable mutations. http://dinglab.wustl.edu/depo.
Medical subject headings
- Databases, Factual
- Medical Oncology
- Neoplasms
- Precision Medicine