Chromatin-mediated feed-forward auxin biosynthesis in floral meristem determinacy.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 30538233.
- Also identified by DOI 10.1038/s41467-018-07763-0 and PMC identifier 6289996.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
In flowering plants, the switch from floral stem cell maintenance to gynoecium (female structure) formation is a critical developmental transition for reproductive success. In Arabidopsis thaliana, AGAMOUS (AG) terminates floral stem cell activities to trigger this transition. Although CRABS CLAW (CRC) is a direct target of AG, previous research has not identified any common targets. Here, we identify an auxin synthesis gene, YUCCA4 (YUC4) as a common direct target. Ectopic YUC4 expression partially rescues the indeterminate phenotype and cell wall defects that are caused by the crc mutation. The feed-forward YUC4 activation by AG and CRC directs a precise change in chromatin state for the shift from floral stem cell maintenance to gynoecium formation. We also showed that two auxin-related direct CRC targets, YUC4 and TORNADO2, cooperatively contribute to the termination of floral stem cell maintenance. This finding provides new insight into the CRC-mediated auxin homeostasis regulation for proper gynoecium formation.
Medical subject headings
- AGAMOUS Protein, Arabidopsis
- Arabidopsis
- Arabidopsis Proteins
- Chromatin
- Flowers
- Indoleacetic Acids
- Meristem
- Mixed Function Oxygenases
- Transcription Factors