Salivary gland tumors: Molecular characterization and therapeutic advances for metastatic disease.
review · Level V
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- Record sourced from PubMed, PMID 30552848.
- Also identified by DOI 10.1002/hed.25468.
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Abstract
Salivary gland cancers represent a rare group of tumors composed by over 20 histological subtypes. Initially treated as one single disease, its diagnosis, prognosis, and treatment are currently being stratified based on morphology. More recently, insight has been provided on the molecular characterization of each subtype, further improving diagnostic accuracy and paving the way for personalized therapy. In this article, we provide a comprehensive review of recent breakthroughs, preliminary results of novel therapy, and future directions on the treatment of these complex malignancies.
Medical subject headings
- Salivary Gland Neoplasms