New vascular insights into premature aging.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 30561385.
- Also identified by DOI 10.1172/JCI125616 and PMC identifier 6355212.
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Abstract
Hutchinson-Gilford progeria syndrome (HGPS) is a fatal disease characterized by premature aging in which young children fail to thrive and adolescents die from myocardial infarction or stroke. The pathogenesis of HGPS is studied intensively because the mechanisms of premature aging may lead to a better understanding of normal aging. In this issue of the JCI, Osmanagic-Myers and colleagues identify the cellular mechanisms that lead to vascular abnormalities and death in children with HGPS.
Medical subject headings
- Myocardial Infarction
- Progeria
- Stroke