Seizure associated with olanzapine.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 30598964.
- Also identified by DOI 10.4103/jfmpc.jfmpc_405_16 and PMC identifier 6259505.
- Licence recorded as CC BY-NC-SA.
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Abstract
Atypical antipsychotics are known to be associated with electroencephalogram abnormalities. Olanzapine can lower seizure threshold and induce epileptiform discharges. However in patients on Olanzapine for the treatment of a primary psychiatric disorder, clinical seizure is a rare occurrence. We report the case of a 23-year-old female with mild mental retardation with schizophrenia with obsessive compulsive disorder who developed new-onset generalized tonic-clonic seizure probably due to Olanzapine. Electroencephalogram showed epileptiform discharges. The seizure risk associated with Olanzapine was reviewed.