A practical guide to biomarkers for the evaluation of colorectal cancer.
Where this comes from
- Record sourced from PubMed, PMID 30600322.
- Also identified by DOI 10.1038/s41379-018-0136-1.
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Abstract
Evaluation of microsatellite instability (MSI) of every colorectal cancer (CRC) is important for prognostic and therapeutic purposes, while molecular testing helps identify actionable targeted therapy for patients with metastatic disease. This review will discuss the biomarkers commonly encountered in the clinical evaluation of CRC, and practical issues regarding MSI screening, reporting, interpretation, molecular test indication, and specimen requirements.
Medical subject headings
- Biomarkers, Tumor
- Colorectal Neoplasms
- Microsatellite Instability