Competition for Food Drives Stem Cell Fate in Facultative Niches.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 30609395.
- Also identified by DOI 10.1016/j.stem.2018.12.010.
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Abstract
Mechanisms regulating maintenance of the stem cell pool in facultative niches of the mammalian testis are poorly understood. In this issue of Cell Stem Cell, Kitadate et al. (2019) propose a minimal model in which stem cells compete for limited resources of fibroblast growth factors, which predicts their density during homeostasis and regenerative conditions.
Medical subject headings
- Mitogens
- Stem Cells