Editorial Commentary: Platelet-Rich Plasma Details Are Critical to Outcome…Catching Is Always Better Than Fishing.

Abstract

The use of platelet-rich plasma (PRP) and the spectrum of orthobiological interventions has been a major innovation in orthopedic surgery and medicine. Biological-based therapies for musculoskeletal disorders and injuries have gained popularity in the past decade and created significant expectation as the future of sports medicine, based on theoretical advantages including minimal invasiveness, greater healing potential, faster recovery, and a less expensive alternative to surgery. These therapies for musculoskeletal intervention include PRP, bone marrow aspirate concentrate, cellular-based therapies, and tissue engineering. Surgeons must always identify and respect the gap between hope, knowledge, and evidence to be successful and efficient in the care of patients. Age, body mass index, and dietary factors may have significant impact on the performance of PRP as a therapeutic intervention. It is imperative that the clinician be armed with a meticulous, comprehensive, and refined technique, protocol, and algorithm to be successful in the use of the PRP.