Predicting the early risk of chronic kidney disease in patients with diabetes using real-world data.

Ravizza, Stefan; Huschto, Tony; Adamov, Anja; Böhm, Lars; Büsser, Alexander; Flöther, Frederik F; Hinzmann, Rolf; König, Helena et al. · Nat Med · 2019

retrospective_cohort · Level III

Where this comes from

Abstract

Diagnostic procedures, therapeutic recommendations, and medical risk stratifications are based on dedicated, strictly controlled clinical trials. However, a plethora of real-world medical data exists, whereupon the increase in data volume comes at the expense of completeness, uniformity, and control. Here, a case-by-case comparison shows that the predictive power of our real world data-based model for diabetes-related chronic kidney disease outperforms published algorithms, which were derived from clinical study data.

Medical subject headings