A "Connexin" Responsible for the Fatal Attraction of Cancer to Bone.
Where this comes from
- Record sourced from PubMed, PMID 30625309.
- Also identified by DOI 10.1016/j.cmet.2018.12.014 and PMC identifier 6443097.
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Abstract
Tumor cell interactions with the bone microenvironment are vital for the establishment and progression of bone metastases. Recently in Cancer Cell, Wang et al. (2018) showed that cells of the osteoblast lineage are critical for the delivery of calcium to tumor cells through gap junctions, pointing toward potential therapies for bone metastases.
Medical subject headings
- Calcium
- Neoplasm Micrometastasis