Isolated Antenatal Hydrocephalus After Fetal Exposure to Misoprostol: Teratogenic Effect of the Cytotec?
case_report · Level V
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- Record sourced from PubMed, PMID 30639481.
- Also identified by DOI 10.1016/j.wneu.2018.12.177.
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Abstract
Misoprostol is often used for termination of pregnancy in France and other countries. However, some pregnancies are continued after taking the drug and congenital malformations are known to be the consequence of fetal exposure to misoprostol, among them hydrocephalus. The type of hydrocephalus in case of misoprostol exposure is not known. We report the first case in the literature of an obstructive hydrocephalus due to an aqueduct of Sylvius stenosis diagnosed during pregnancy after misoprostol intake. The possible physiopathologic implications of the drug regarding the genesis of this malformation are discussed.