Addressing Challenges in Developing a Core Domain Set in Adherence Interventions in Rheumatology: A Report from the OMERACT-Adherence Group.

Kelly, Ayano; Bartlett, Susan J; de Wit, Maarten P; Beaton, Dorcas E; Dawson, Therese; Evans, Vicki; Gill, Michael; Hassett, Geraldine et al. · J Rheumatol · 2019

other · Level V

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Abstract

The OMERACT-Adherence meeting was convened to discuss the conceptual and methodological challenges in developing a core domain set (Adherence-CDS) for trials of interventions for medication adherence in rheumatology. Forty participants from nine countries participated. Four ideas emerged: for adherence trials, the Adherence-CDS could include adherence and the condition-specific CDS; many factors affect adherence and are intervention targets, contextual factors, or outcome domains; adherence is a critical factor in drug trials; and standardized adherence measures are needed. Despite the challenges, the meeting clarified an approach to developing an Adherence-CDS that complements existing OMERACT work and methodology.

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