Association of Smoking and Obesity on the Risk of Developing Primary Sjögren Syndrome: A Population-based Cohort Study.
case_control · Level III
Where this comes from
- Record sourced from PubMed, PMID 30647188.
- Also identified by DOI 10.3899/jrheum.180481 and PMC identifier 6606330.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
To explore the role of smoking and obesity in primary Sjögren syndrome (pSS). Olmsted County (Minnesota, USA) residents (n = 106) diagnosed with pSS from 2000 to 2015 were compared to 3 controls without pSS and matched for age and sex who were randomly selected from Olmsted County residents. Current smokers were less likely to be pSS cases (OR 0.34, 95% CI 0.14-0.85), while there was no association between former smoking and case/control status (OR 1.27, 95% CI 0.80-2.03) compared to never smokers. Smoking status was not associated with antinuclear antibody, anti-SSA, anti-SSB, or rheumatoid factor positivity (p > 0.05). OR for obesity was 0.79 (95% CI 0.48-1.30). In this population-based study, current smoking was inversely associated with case/control status, while body mass index lacked any association.
Medical subject headings
- Obesity
- Sjogren's Syndrome
- Smoking