PSiTE: a Phylogeny guided Simulator for Tumor Evolution.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 30649258.
- Also identified by DOI 10.1093/bioinformatics/btz028.
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Abstract
Simulating realistic clonal dynamics of tumors is an important topic in cancer genomics. Here, we present Phylogeny guided Simulator for Tumor Evolution, a tool that can simulate different types of tumor samples including single sector, multi-sector bulk tumor as well as single-cell tumor data under a wide range of evolutionary trajectories. Phylogeny guided Simulator for Tumor Evolution provides an efficient tool for understanding clonal evolution of cancer. PSiTE is implemented in Python and is available at https://github.com/hchyang/PSiTE. Supplementary data are available at Bioinformatics online.
Medical subject headings
- Neoplasms
- Software