Differences in HbA<sub>1C</sub> at the time of diabetes diagnosis in the adult population of Ontario, Canada.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 30679144.
- Also identified by DOI 10.1016/j.pcd.2018.12.008.
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Abstract
To determine the proportion of adults with HbA<sub>1c</sub>≥8.0% (64mmol/mol) at diabetes diagnosis, as an indicator of delayed diagnosis or less intensive screening. We conducted a cross-sectional population-level study using clinical, administrative and immigration data from Ontario, Canada. We identified all individuals diagnosed with diabetes between June 2012 and June 2015, and determined the HbA<sub>1c</sub> between 60days prior to and 30days after diagnosis. Individuals were stratified based on many sociodemographic, clinical and primary care characteristics, and the proportion with HbA<sub>1c</sub>≥8.0% (64mmol/mol) was determined. Mean HbA<sub>1c</sub> at diabetes diagnosis in the population was 7.3±1.9% (56±21mmol/mol), and 21.1% had HbA<sub>1c</sub>≥8.0% (64mmol/mol) at diagnosis. Factors for which there were important differences in the proportion with HbA<sub>1c</sub>≥8.0% (64mmol/mol) included age, sex, ethnicity, comorbidities, frequency of primary care and primary care rostering. In a real-world population-level setting, more than one-fifth of individuals diagnosed with diabetes have HbA<sub>1c</sub> levels ≥8.0% (64mmol/mol), suggesting a delay in diagnosis due to inadequate screening. Differences were found based on age, sex and clinical factors, but not based on socioeconomic or immigration factors.
Medical subject headings
- Diabetes Mellitus
- Glycated Hemoglobin
- Mass Screening