Receptor Structures for a Caldron of Cannabinoids.

Lorenzen, Emily; Sakmar, Thomas P · Cell · 2019

basic_science · Level V

Where this comes from

Abstract

Structures of the cannabinoid receptor 1 (CB1) in complex with an "ultrapotent" synthetic cannabinoid and its G protein (Krishna Kumar et al., 2019) and CB2 in complex with a new rationally designed inverse agonist (Li et al., 2019) provide unique snapshots of the molecular pharmacology of cannabinoids.

Medical subject headings